In this blog post, I will review the current recommendation of endocrine therapy for early non-metastatic breast cancer hormone positive breast cancer (Estrogen receptor positive ER + and/or Progesterone receptor positive PR +), this is most often referred to as Adjuvant hormonal or Adjuvant Endocrine therapy, for discussion regarding the use of endocrine therapy for metastatic breast cancer please refer to my earlier post by clicking here.
Hormone receptor-positive Breast cancer comprise 75% of all cases.
Endocrine therapy is of significant benefit and Generally well tolerated.
Continue reading “Endocrine Therapy for Early Breast Cancer”
Bone health among breast cancer survivors continues to be a heavily debated subject in medical oncology with many developments occurring during the past decade. Skeletal complications in breast cancer patient can be caused chemotherapy-induced ovarian failure, use of gonadotropin-releasing hormone (GnRH) agonists, surgical oophorectomy, and use of AI’s all of the above can cause bone loss and increased risk for fractures, however in this blog post, I will focus my discussion on bone toxicity caused by aromatase inhibitors (AI) such as anastrozole, letrozole, and exemestane. With the increasing use of AI’s in postmenopausal women, as well as, the use of AI’s in combination with GnRH agonist agents in premenopausal women, oncologists are now more than ever required to have a deep understanding of bone loss associated with AI’s (AIBL) and taking measures to help prevent such complication. For a patient-oriented discussion of bone health please click here.
Women receiving aromatase inhibitor therapy are at increased risk for fractures.
Continue reading “Bone Health in Breast Cancer Survivors.”